Quake Challengers South America Qualifier was the South American qualifier for Quake Pro League Season 4, featuring eight players in Quake Champions Time Limit Duel. The tournament used a single-elimination bracket with best-of-three matches. Full brackets, match results and VODs are available on the tournament page.

The qualifier awarded one QWC 2023 slot, claimed by Yup after he finished ahead of Cirux.